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Heartworm & other anti-parasitic meds
Ivormectin for heartworm prevention | Other meds | Diluting Ivomec
Ivermectin is the ingredient in Heartgard - the popular heartworm prevention medicine. Yet the actual medicine in it costs less than a penny.



Heartgard also contains pyrantel pamoate; an inexpensive dewormer. Like ivormectin, you may buy pyrantel pamoate in bulk at inexpensive cost.

This page is focused only on heartworm prevention because the consequence of letting my German Shepherd ever contract such a nasty parasite is scary.

But, yes, I give Tyler other medications such as KP Advantix, Frontline Plus, and Revolution.
Prevention of heartworm infection ...ivermectin (sold under the brand name Heartgard...), milbemycin ...Advantage Multi (imidacloprid + moxidectin) Topical Solution, which utilizes moxidectin for control and prevention of roundworms, hookworms, heartworms, whipworms, as well as imidacloprid to kill adult fleas. Selamectin (Revolution), ...also controls fleas, ticks, and mites.

Preventive drugs ...protect more than 99 percent of dogs and cats from heartworm. Most compromises in protection result from failure to properly administer the drugs during seasonal transmission periods. In regions where the temperature is consistently above 14 C (57 F) year round, a continuous prevention schedule is recommended.

It has been shown that lapses of up to 4 months between doses of Ivermectin-based products still provides 95% protection from adult worms. ...

Heartworm prevention for cats is available as ivermectin (Heartgard for Cats), ...or the topical selamectin (Revolution for Cats).

Annual testing for heartworms ...ensuring that prophylaxis is achieved ...first ensure that the dog is free of heartworm infection. ...most practitioners retest at six months to coincide with refilling prescriptions and performing semiannual exams. ...subsequent antigen testing should be performed on the one-year anniversary date of the initial test and annually thereafter...precisely determine if a dog is infected...testing can be performed ...again four months later. ...an antigen test may be positive as early as five months after infection...

...note that a negative antigen test at four months ..does not ensure that a dog was negative ..at the time of starting, resuming or changing any preventive therapy.

Preventives...ivermectin, milbemycin oxime, moxidectin or selamectin ...will eventually clear microfilariae from the blood of most dogs with patent infections...by the drugs...microfilaricidal effect...retard repopulation by gradually suppressing embryogenesis.
Medications I use on Tyler to prevent fleas, ticks, heartworms etc.
I rotate medications such as Advantix and Frontline since they contain different medicines; parasites might develop a tolerance. If I give him Revolution one month I don't give him ivermectin since Revolution is the heartworm preventative for that month. My rule is to give Tyler a flea & tick med + a heartworm med every month ; either Revolution alone; or Advantix + ivermectin; or Frontline + ivermectin. If you have comments on this let me know?
K9 Advantix (ebay - $44/4 doses)
Frontline Plus (eBay - $36/4 doses)
Revolution (from Canada; $96/6 doses)
Ivermectin (make my own dilution; 2 cents/dose)

eBay is a good place to pick them up at discount; I purchased a 4X of K9 Advantix for $44 including shipping. I also bought Frontline Plus, large dog size, 4 doses for $36. These are great prices when I compare to what they charge at local vets or pet stores,

Revolution is about $16/month at the best price discounts online but REQUIRES A PRESCRIPTION. So screw that! Buy it from Canada.

Many vets want to profit by selling Revolution to you directly for $30/dose. That is $360/year.

If you visit a vet to get Revolution you should insist on a 6 or 12 month prescription for Revolution to take away with you - just as a regular doctor gives you a prescription to take away. Then you can buy Revolution from your choice of best price online providers. DO NOT BUY IT FROM THE VET AT THEIR MARKUP PRICE!

Search online for the cost of Revolution and mail them the prescription. (Make a copy for back up before you mail it).

See Google for " revolution for dogs without prescription" & buy directly from Canada.

If my vet refuses to give me a take home prescription, I 'd look for a new vet. I won't be pushed around by vets trying to make money from poor people like myself.
Veterinarians who fish for money
Watch out for the paperwork the front office person asks you to fill out. One vet I took Tyler to had a section with questions such as

"Do you believe your dog deserves the best medical care money can buy?" [I checked
NO ]

"My dog is a well loved member of the family"
[I wrote in my own box & checked-
He's a dog! ]

Vets are trained (they take marketing courses in vet school, read books on how to have a highly profitable practice, etc.) to dig around in your pockets to see how much money you will part with. Cat lovers pay more for services than dog owners based on the assumption that cat lovers will pay more for " Sweet little kitty cat..."

Just do a Google search on "money grubbing veterinarians" and form your own opinions. [return]
From "Profit Profile" advice for Vets to make more money
Send a reminder post card, then a reminder letter. After the reminder letter have a staff member call and express concern that the pet is getting all the medical care needed. This should be scripted... it lets past clients know you are concerned ... about their pets medical care. 75% - 89% of clients do not care about price when picking and staying with a veterinarian...85% 90% of clients state that they are extremely happy with their veterinarian and wouldnt change even if price was cheaper at another price. [more...]
Revolution (Selamectin) is a topical, once-monthly pet medication distributed by Pfizer and manufactured in an undisclosed country, that prevents heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. The active ingredient, Selamectin, which causes paralysis and eventual death in the aforementioned parasites, has tested positively as recently as 2023. Revolution is waterfast, and does not lose its effectiveness with bathing. It is packaged according to its varying dosage sizes, and is applied once monthly.

Selamectin is a topical (applied to the skin) insecticide and heartworm preventive. It is also used to treat ear mites, demodectic (red) mange and sarcoptic mange (scabies). Temporary irritation or hair loss at the application site may be seen.
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Advantage (Imidacloprid) Imidacloprid is another relatively new insecticide, which is in yet a different class of chemicals. Imidacloprid interferes with the nerve conduction system of insects. Imidacloprid acts by blocking the nerve receptors. It kills fleas, but does not have activity against ticks. Imidacloprid is mixed with an oil carrier and the drug collects in the hair follicles from which it is slowly released. Safety: Imidacloprid has a wide margin of safety, but as with all other pesticides, some pets may develop sensitivity to the product.
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Frontline (Arylheterocycles) Fipronil is the most commonly used product in this relatively new group of synthetic insecticides, such as Frontline Top Spot. Arylheterocycles block the passage of chlorine through cells in the insect's nervous system and this results in paralysis. Fipronil is most commonly used as a once-a-month topical insecticide on cats and dogs to kill fleas and ticks. Fipronil is generally mixed with an oil carrier and the drug collects in the hair follicles from which it is slowly released. Safety: As with any pesticide, some animals may show a temporary sensitivity where the product is applied. Some animals may also develop more severe sensitivities, and if so, a veterinarian should be consulted.
Ivormectin for heartworm prevention | Other meds | Diluting Ivomec
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